====== tmle.npvi software home page ======

===== Overview =====

  * **Title**: Targeted Learning of a Non-Parametric Variable Importance Measure of a Continuous Exposure
  * **Language**: ''R''
  * **Description**: Targeted minimum loss estimation (TMLE) of a non-parametric variable importance measure of a continuous exposure 'X' on an outcome 'Y', taking baseline covariates 'W' into account.
  * **Authors**: [[http://www.math-info.univ-paris5.fr/~chambaz/|Antoine Chambaz]] and [[members:pneuvial:welcome|Pierre Neuvial]]
  * **Maintainer**: [[members:pneuvial:welcome|Pierre Neuvial]]
  * **Availability**: get [[https://cran.r-project.org/web/packages/tmle.npvi/|tmle.npvi]] from CRAN
  * **References**: 
      * Chambaz, A., Neuvial, P., & van der Laan, M. J. (2012). [[https://projecteuclid.org/euclid.ejs/1340369355|Estimation of a non-parametric variable importance measure of a continuous exposure]]. //Electronic Journal of Statistics//, 6, 1059.
      * Chambaz, A. & Neuvial, P. (to appear). [[https://hal.archives-ouvertes.fr/hal-01113680/|tmle. npvi: targeted, integrative search of associations between DNA copy number and gene expression, accounting for DNA methylation]]. //Bioinformatics//. 

=====  Installation =====

The package is available from R-forge and can be installed as follows from within ''R'':
<code>
install.packages("tmle.npvi")
</code>

===== Package vignettes ===== 

In ''R'',

<code>
library("tmle.npvi")
vignette("tmle.npvi")
</code>