====== Guillem Rigaill ====== {{:members:grigaill:photoglm.png?150|}} **Senior research scientist at INRAE** (aka directeur de recherche). \\ Research interests: Machine Learning, Statistics, and Applications to Molecular Biology. \\ I work between a statistics team and a bioinformatics team: \\ 1) [[http://www.math-evry.cnrs.fr/sg/welcome|Stat & Genome]], Laboratoire de Mathématiques et Modélisation d'Évry (LaMME) \\ 2) [[http://ips2.u-psud.fr/en/research/pmin-department-plant-microbe-interactions-and-networks-biotic-interactions/gnet-genomics-networks.html|Genomics Networks Team]], Institut des Sciences des Plantes de Paris-Saclay (IPS2) \\ ☎ +33 (0) 1 64 85 35 44 \\ \\ {{:members:grigaill:rigaill_cv_en092020.pdf|Curriculum Vitae}}\\ [[https://scholar.google.com/citations?user=Ve7EEQgAAAAJ&hl=en|List of publications on Google Scholar]] \\ [[https://orcid.org/0000-0002-7176-7511|ORCID]] \\ ===== Research Themes ===== My research focuses on the development of statistical models, statistical methods, and algorithms for the analysis and interpretation of high-throughput biological data. 1. Modeling and inferring dependence in big data settings * Models: Multiple changepoints, Clustering, Regression * Methods: Dynamic Programming, Convex relaxation, Penalized Likelihood 2. Applications in molecular biology and bioinformatics * RNA analysis (RNA-seq, RNA-footprinting, RIP-seq...), Chip-Seq, DNA copy-number analysis * Practical evaluation of statistical tools for genomics \\ ===== A Few Recent Publications ===== A list of my publications can be found on [[https://scholar.google.com/citations?user=Ve7EEQgAAAAJ&hl=en|Google Scholar]]. \\ *[2025] Online Multivariate Changepoint Detection: Leveraging Links With Computational Geometry. \\ L. Pishchagina, G. Romano, P. Fearnhead, V. Runge and __G. Rigaill__. \\ **Journal of the Royal Statistical Society Series B: Statistical Methodology** [[https://academic.oup.com/jrsssb/advance-article-abstract/doi/10.1093/jrsssb/qkaf046/8223216?utm_source=advanceaccess&utm_campaign=jrsssb&utm_medium=email|Journal]] [[https://arxiv.org/abs/2311.01174|ArXiv]] *[2024] Ms. FPOP: an exact and fast segmentation algorithm with a multiscale penalty. \\ A. Liehrmann, __G. Rigaill__. \\ **Journal of Computational and Graphical Statistics** [[https://www.tandfonline.com/doi/full/10.1080/10618600.2024.2402895|Journal]] and [[https://arxiv.org/abs/2303.08723|ArXiv]] *[2023] Fast online changepoint detection via functional pruning CUSUM statistics. \\ G. Romano, I.A. Eckley, P. Fearnhead, and __G. Rigaill__. \\ **Journal of Machine Learning Research** [[https://www.jmlr.org/papers/volume24/21-1230/21-1230.pdf|Journal]] and [[https://arxiv.org/abs/2110.08205|ArXiv]] *[2023] DiffSegR: an RNA-seq data driven method for differential expression analysis using changepoint detection. \\ A. Liehrmann, E. Delannoy, A. Launay-Avon, E. Gilbault, O. Loudet, B. Castandet and __G. Rigaill__. \\ **NAR Genomics and Bioinformatics** [[https://academic.oup.com/nargab/article/5/4/lqad098/7369456|Journal]] *[2023] Adjusting the adjusted Rand Index: A multinomial story. \\ M. Sundqvist, J. Chiquet, __G. Rigaill__. \\ **Computational Statistics** [[https://link.springer.com/article/10.1007/s00180-022-01230-7|Journal]] [[https://arxiv.org/abs/2011.08708|ArXiv]] ===== My Habilitation and Ph.D ===== **Habilitation (a.k.a HDR) in applied Mathematics** in 2020 at the [[https://www.universite-paris-saclay.fr/en/doctoral-schools/hadamard-doctoral-school-mathematics|Hadamard Doctoral School of Mathematics]] My manuscript (in French) and slides are here: * [[https://tel.archives-ouvertes.fr/tel-02955535|HDR-Manuscript]] * {{:members:grigaill:Pres_18092020.pdf|HDR-Slides}} **Ph.D.in applied Mathematics** in 2010 at the [[https://abies.agroparistech.fr/|ABIES Doctoral School]] My manuscript (in English) is here: * [[https://tel.archives-ouvertes.fr/pastel-00593939|PhD-Manuscript]]