logiciels:drimm:help

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+ | ====== Help DRIMM ====== | ||

+ | This program is dedicated to the estimation and the use of Drifting Markov Models (DMM). | ||

+ | |||

+ | ===== Two different ways to use ===== | ||

+ | |||

+ | |||

+ | - DMM is estimated on a sequence. | ||

+ | - DMM is given in a model file. | ||

+ | |||

+ | ===== Description of parameters ===== | ||

+ | |||

+ | ** -SpM ** Estimation by splines M. -N must be used.\\ | ||

+ | |||

+ | **-SpH ** Estimation by splines H. -N and -Nar must be used. | ||

+ | |||

+ | **-Spl** Estimation by splines. -N and -Nar must be used. | ||

+ | |||

+ | **-Poly** Estimation by polynom (stochastic matrices). | ||

+ | |||

+ | ** -PolyM** Estimation by polynom (no stochastic matrices). | ||

+ | |||

+ | ** -out <basename> ** Basename for all output files. Output 'basename.config_<num>.out' with -s. Output 'basename.config_sm.out' with -sm. Output 'basename.config_ss.out' with -ss. Output 'basename.config.out' with -cf. | ||

+ | |||

+ | ** -a <alphabet_file> ** A file describing the alphabet to use. | ||

+ | |||

+ | **-s <sequence_file>**A file containing file of sequences. DMM is estimated on each sequence (Use 1). At least one of -s or -sm or -ss must be used | ||

+ | |||

+ | **-sm <sequence_mean_file>** A file containing file of sequences. DMM is estimated as a mean of DDM on each sequence (Use 1). At least one of -s or -sm or -ss must be used | ||

+ | |||

+ | |||

+ | ** -ss <sequence_sum_file> **A file containing file of sequences. DMM is estimated over all the sequences (Use 1). At least one of -s or -sm or -ss must be used | ||

+ | |||

+ | ** -order <order>=0>**Order of the DMM (Use 1). Order must be > 0 with -SpM or -SpH. | ||

+ | |||

+ | ** -deg <degree>=0> ** Degree of the DMM (Use 1). Degree is useless with -SpH and -Spl. Degree is 3. | ||

+ | |||

+ | **-N <Number of segments>0> ** Number of segments in the case of estimation by splines. | ||

+ | |||

+ | **-Nar <Number of segments>0> ** Number of aller retour with -Spl and -SpH. | ||

+ | |||

+ | **-cf <model_file> ** DMM is given by the <model_file> (Use 2). Must be used with -Poly, -PolyM, -Spl, -SpM, or -SpH. | ||

+ | |||

+ | ** -L ** Compute the log-likelihood on the estimated sequences (Use 1). Can not be used with -sm or -ss | ||

+ | |||

+ | **-AIC **Compute the AIC on the estimated sequences (Use 1). Can not be used with -sm or -ss | ||

+ | |||

+ | **-BIC **Compute the BIC on the estimated sequences (Use 1). Can not be used with -sm or -ss | ||

+ | |||

+ | **-l <sequence_file_l> **Compute the log-likelihood on <sequence_file_l>. | ||

+ | |||

+ | **-aic <sequence_file_aic>**Compute the aic on <sequence_file_aic>. | ||

+ | |||

+ | **-bic <sequence_file_bic> ** Compute the bic on <sequence_file_bic>. | ||

+ | |||

+ | **-law **Compute the stationary law of the DMM. basename.trace_stat_<num>.out is an output containing the stationary law. <num> is an integer designing the number of the sequence. | ||

+ | |||

+ | |||

+ | **-slaw <in>0> <out>0> ** Compute the stationary law of the DMM between <in> and <out>. basename.trace_stat_segment_<num>.out is an output containing the stationary law. <num> is an integer designing the number of the sequence. | ||

+ | |||

+ | |||

+ | **-dist ** Compute distributions of the DMM. basename.trace_dist_<num>.out is an output containing the distributions. <num> is an integer designing the number of the sequence. | ||

+ | |||

+ | |||

+ | **sdist <in>0> <out>0>** Compute the distribution of the DMM between <in> and <out>. basename.trace_dist_segment_<num>.out is an output containing the distributions. <num> is an integer designing the number of the sequence. | ||

+ | |||

+ | |||

+ | **-pi ** Return files 'basename.Pit_<num>.out' or 'basename.Pit_sm.out' or basename.Pit.out' or 'basename.Pit_ss.out' containing the matrix Pi_t for all t. <num> is an integer designing the number of the sequence | ||

+ | |||

+ | |||

+ | **-simu** Return files 'basename.simulation_<num>.out' or 'basename.simulation_sm.out' or 'basename.simulation_ss.out' or basename.simulation.out' containing a sequence simulated by the DMM. <num> is an integer designing the number of the sequence. | ||

+ | |||

+ | **-nv** Mode 'not verbose'. | ||

+ | |||

+ | **-h ** Print this help. | ||

+ | |||

+ | ===== Examples ===== | ||

+ | |||

+ | DRIMM -Poly -order 1 -deg 2 -a dna.alpha -s lambda.fa -out lambda | ||

+ | |||

+ | for the estimation of a polynomial DMM (order 1 and degree 2) on the phage Lambda. | ||

+ | |||

+ | DRIMM -SpM -N 2 -order 1 -deg 3 -a dna.alpha -s lambda.fa -out lambda | ||

+ | |||

+ | |||

+ | for the estimation of a DMM with polynomial splines (order 1 and degree 3 with 2 segments) on the phage Lambda. |

logiciels/drimm/help.txt · Last modified: 2014/11/28 15:51 (external edit)

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