Alia Dehman

Doctorante (UEVE)
Université d'Évry Val d'Essonne
Laboratoire de Mathématiques et Modélisation d'Évry (UMR 8071)
I.B.G.B.I., 23 Bd. de France, 91037 Évry Cedex
☎ +33 (0) 1 64 85 35 36
📠: +33 1 64 85 36 01
Firstname.Lastname@genopole.cnrs.fr

Topic of the thesis

I am working on incorporating the linkage disequilibrium (LD) information in Genome-Wide association studies.

Research topics

Genome-Wide Association Studies (GWAS)

Linkage Disequilibrium (LD)

Structured penalized regression models

Publications

2019
[1]	Ambroise, C., Dehman, A., Neuvial, P., Rigaill, G. & Vialaneix, N. Adjacency-constrained hierarchical clustering of a band similarity matrix with application to Genomics. Algorithms for Molecular Biology, 14:22, BioMed Central, 2019.
[2]	Ambroise, C., Dehman, A., Neuvial, P., Rigaill, G. & Vialaneix, N. Adjacency-constrained hierarchical clustering of a band similarity matrix with application to genomics. , 2019., (Poster).
2018
[3]	Ambroise, C., Dehman, A., Koskas, M., Neuvial, P., Rigaill, G. & Vialaneix, N. Adjacency-constrained hierarchical clustering of a band similarity matrix with application to genomics. In Journée Régionale de Bioinformatique et Biostatistique, Génopole Toulouse, 2018.
2015
[4]	Dehman, A. Spatial Clustering of Linkage Disequilibrium blocks for Genome-Wide Association Studies. , 2015. (Theses)
[5]	Dehman, A., Ambroise, C. & Neuvial, P. Performance of a blockwise approach in variable selection using linkage disequilibrium information. BMC Bioinformatics, 16:14, BioMed Central, 2015.
2013
[6]	Dehman, A., Ambroise, C. & Neuvial, P. Incorporating linkage disequilibrium blocks in Genome-Wide Association Studies. In JOBIM proceeding 2013, ():, , 2013.
[7]	Dehman, A. Incorporating Linkage Disequilibrium Blocks in Genome-Wide Association Studies. , 2013.

Seminars and Posters

Statistics for Systems Biology (SSB), Evry, June 2013

Slides slides_ssb

Software and Statistical Methods for Population Genetics (SSMPG), Aussois, 2013

Poster poster_SSMPG

Journées Ouvertes en Biologie, Informatique et Mathématiques (JOBIM), Toulouse, July 2013

Extended abstract ex_abs

Slides slides_jobim

Troisièmes Rencontres R, Montpellier, June 2014 http://r2014-mtp.sciencesconf.org/38324

Software

“Blockwise Approach using Linkage Disequilibrium information” (BALD) :

The BALD R package provides functions for the Genome-Wide Association Studies including simulation of SNPs data, constrained hierarchical clustering using Linkage Disequilibrium (LD) measures, the Gap statistic to find the optimal number of clusters, and statistical regression models for SNP selection (Univariate, Lasso, Group Lasso, Elastic-Net).

Package source : http://www.math-evry.cnrs.fr/logiciels/bald

Teaching

L1 Bio: Analysis

L2 Math and L2 Info: Probabilities and Statistics

A competition award

The Audience Award in the local stage of the competition “Ma thèse en 180 secondes” in Evry MT180-Evry.

Internship

M2 internship report Régression parcimonieuse structurée pour les études d’association pangénomiques

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